Final Editorial (2023)
نویسندگان
چکیده
منابع مشابه
Dmd053322 2018..2023
In vitro–in vivo correlation (IVIVC) of intrinsic clearance in preclinical species of rat and dog was established using the hepatocyte relay method to support high-confidence prediction of human pharmacokinetics for low-clearance compounds. Good IVIVC of intrinsic clearance was observed for most of the compounds, with predicted values within 2-fold of the observed values. The exceptions involve...
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I n 12 years, the Journal of Rehabilitation Research and Development (JRRD) has transformed from a small Department of Veterans Affairs (VA) house-organ into a leading international rehabilitation research publication , benefitting Veterans, all persons with disabilities, and those who care for them. At JRRD, we have fully honored U.S. Public Law 729 passed in 1948, which established the origin...
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Introduction Chronic asymptomatic iridocyclitis occurs in 10-20% of all patients with JIA leading to insidious but progressive morbidity and possible blindness. Patients with JIA-associated uveitis need to be seen by an ophthalmologist regularly. Lean thinking is based upon the following principles 1) Identifying the customer value (value adding steps) and alleviating the redundant parts of the...
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Cerlapirdine (SAM-531, PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine and other 5-HT6 receptor antagonists have been in clinical development for the symptomatic treatment of Alzheimer’s disease. A human absorption, distribution, metabolism, and excretion study was conducted to gain further understanding of the metabolism and disp...
متن کاملDev104240 2014..2023
Tissue homeostasis is maintained by adult stem cells, which selfrenewand give rise to differentiating cells. The generation of daughter cells with different fates is mediated by signalling molecules coming from an external niche or being asymmetrically dispatched between the two daughters upon stem cell mitosis. In the adult Drosophila midgut, the intestinal stem cell (ISC) divides to generate ...
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ژورنال
عنوان ژورنال: Journal of Loss & Trauma
سال: 2023
ISSN: ['1532-5024', '1532-5032']
DOI: https://doi.org/10.1080/15325024.2022.2161151